Christina Applegate shares health update after revealing MS misdiagnosis

Christina Applegate has revealed that doctors confirmed she was misdiagnosed with MS, a diagnosis she received in 2021. Now, after years of living with persistent symptoms, she faces a new journey to find out what is really causing them.

Returning to her podcast “MeSsy,” Applegate dedicated a two-part episode to explaining the situation and sharing with listeners that she had been misdiagnosed.

“This may come as great news, but to me, I’m back at square one,” she said, according to Variety. “It’s hard to say that [my doctor] came into my room and she said, ‘Congratulations, you don’t have MS.’”

She went on to describe why she was “not happy at all” about it: “You don’t get misdiagnosed and then all of the sudden I’m better. I haven’t gotten better … If anything, I’ve gotten worse in some ways,” she said. “So I’m back at square one, that I don’t know what’s going on with me.”

The symptoms that led to her MS diagnosis in 2021 have persisted, and she now faces a new journey to uncover what is causing them.

Christina Applegate misdiagnosed MS

In the years since her diagnosis, Applegate has spoken candidly about losing abilities she once took for granted.

“My life isn’t wrapped up with a bow,” she told People in February while discussing her bestselling memoir, “You with the Sad Eyes.”

“People’s lives, sorry for lack of a better term, f***ing suck sometimes. So, I’m being as honest and raw as I possibly can,” she shared, adding that much of her day is spent in bed because movement causes pain.

While speaking on the podcast, she added that “there’s a pretty damn high number of misdiagnoses with MS.”

“So I’m back at square one where I don’t know what’s going on with me, and that’s going to be an online investigation that my doctors are going to be getting into just to find out what has been going on since 2021, why did this happen?”

“I’ve gone through a great depression because of it. But, you know, I lost everything. I lost my job,” she went on, fighting back tears. “God, I’m so sorry, I get really emotional because it stopped my life. I still have to use wheelchairs when I go to the doctor’s office. I can’t walk from the car to the room. I mean, I’m still in this. Nothing magical happened when she said, ‘You don’t have MS.’ Nothing magical happened.”